The relationship between thyroid hormones and lipid profile in subclinical hypothyroidism female patients

Background and objectives: Subclinical thyroid disorder is a most common subclinical disease among many medical conditions such as cardiovascular Lyme disease. The aim of this study was to determine the relationship between lipid profile results, ratios, anthropometric parameters hormones. Methods: One hundred patients (ages 20 50 years) with hypothyroidism (SHT group) healthy subjects (control group), who are age-matched patients, were included in current study. Thyroid function tests (TSH, T3 T4) determined by immunodiagnostic assay system (VIDAS) for all participants. serum glucose evaluated Biolis 24i Premium chemistry analyser. In addition, systolic diastolic blood pressure measured each individual using mercury sphygmomanometer. Results: levels high-density lipoprotein-cholesterol (HDL-c) significantly lower SHT group when compared control group. Whereas, level low-density (LDL-c), ratios total cholesterol (TC)/HDL-c LDL-c/HDL-c higher than controls. Moreover, TSH negatively correlated pressure. Conclusions: Both LDL-c HDL-c altered patients. And, there negative association